BDBM50431381 FOSTAMATINIB::R-788 Free acid::R-935788 Free acid
SMILES COc1cc(Nc2ncc(F)c(Nc3ccc4OC(C)(C)C(=O)N(COP(O)(O)=O)c4n3)n2)cc(OC)c1OC
InChI Key InChIKey=GKDRMWXFWHEQQT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50431381
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Federal University Of Parana
Curated by ChEMBL
Federal University Of Parana
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human ABCG2 expressing membrane vesicles assessed inhibition of BCRP- mediated transport of [3H]estrone 3-sulfate for 2 mins using [3H]...More data for this Ligand-Target Pair